This condition, which can lead to sudden vision loss, has sparked concern among users of the widely prescribed diabetes and weight loss drug.
The Study Findings
The study, published in JAMA Ophthalmology, analyzed medical records of 16,827 patients between 2017 and 2023. Researchers found that:
- Patients with type 2 diabetes using semaglutide had a fourfold increased risk of developing NAION compared to those on other diabetes medications.
- Those taking semaglutide for weight loss exhibited a sevenfold higher risk compared to alternative treatments.
The findings have raised questions about whether the medication’s effects on blood pressure or vascular health could contribute to this risk.
What is NAION?
NAION is a rare condition that occurs when blood flow to the optic nerve is disrupted, leading to sudden, painless vision loss in one eye. Common risk factors include diabetes, hypertension, and sleep apnea—conditions already prevalent among patients prescribed semaglutide.
Unfortunately, there are currently no effective treatments for NAION, making prevention and early detection critical.
Expert Reactions
Dr. Joseph Rizzo, senior author of the study and director of the Neuro-Ophthalmology Service at Mass Eye and Ear, noted, “While our findings suggest an association, causation has not yet been established.” He emphasized the need for further research to confirm these results and understand the mechanisms involved.
Organizations like the American Academy of Ophthalmology have advised patients not to discontinue semaglutide without consulting their healthcare providers but recommend immediate medical attention for any sudden vision changes.
Manufacturer’s Response
Novo Nordisk, the manufacturer of Ozempic and Wegovy, acknowledged the study’s findings but highlighted its limitations. In a statement, the company said, “NAION is not listed as a known adverse reaction in the current product labeling,” adding that patient safety remains their priority.
What Patients Should Do
For now, semaglutide remains an effective treatment for type 2 diabetes and weight loss. However, patients should:
- Be aware of the potential risks associated with the medication.
- Report any sudden vision changes to their doctor immediately.
- Discuss alternative treatment options with their healthcare providers if concerned.
As noted by Reuters, this discovery underscores the importance of ongoing monitoring for potential side effects of widely used medications.
Emma Bennett is a lifestyle enthusiast dedicated to exploring the trends, tips, and ideas that enhance everyday living. From wellness routines and home decor inspiration to personal growth and modern etiquette, Emma provides readers with insights to live a balanced and fulfilling life. Her stories are a blend of creativity and practicality, designed to inspire and empower.
