XS Nightclub has been dark for the last few weeks, but the wait for its return is nearly over. Wynn Nightlife has officially announced the grand reopening of the iconic venue on Thursday, November 5, supported by a massive four-day run of the world’s biggest headliners. The celebration promises to bring the dancefloor back to life, featuring a high-profile lineup that signals a new era for the Las Vegas staple.
The club has been closed for what Wynn describes as a complete reimagining—the first top-to-bottom overhaul since the venue opened on New Year’s Eve 2008. While programming shifted to Encore Beach Club at Night during the construction, the main room has been undergoing significant upgrades. Wynn has remained tight-lipped on specific details, promising only refreshed interiors and new production technology, but the reopening lineup speaks volumes about the scale of this transformation.
Thursday, November 5: RÜFÜS DU SOL [DJ Set]
Opening night is the one to circle, as it marks a rare opportunity to catch RÜFÜS DU SOL in an intimate setting. Following an extensive North American tour that included sold-out nights at Madison Square Garden and headline slots at major festivals, the trio has indicated they will be stepping away from the road for a hiatus. This DJ set at XS offers fans a chance to see the group in a 40,000-square-foot club environment, providing a unique perspective on their sound before they head back to the studio.
Friday, November 6: The Chainsmokers
Few artists share as much history with the venue as The Chainsmokers. Alex Pall and Drew Taggart have been long-time Wynn Nightlife residents, and their return for the reopening weekend underscores their deep connection to the club’s evolution. Having spent recent years leaning back into dance-floor-focused productions, the duo is perfectly positioned to christen the new space.
Saturday, November 7: Calvin Harris
As a cornerstone of the Las Vegas dance music scene, Calvin Harris remains a vital part of the Wynn ecosystem. Under an exclusive two-year deal, XS and Encore Beach Club serve as the only places in Las Vegas to catch the superstar producer. His Saturday night set is expected to be a career-spanning journey through his most iconic records, perfectly suited for the club’s upgraded production capabilities.
Sunday, November 8: Diplo B2B Hugel
The weekend concludes with a high-energy pairing. Diplo, who has played the venue more than almost any other artist, will go back-to-back with Hugel. Known for his infectious Latin house sound, Hugel joins the veteran resident to ensure the reopening weekend ends on a high note.
Wynn has framed this reopening as the next era for the venue, maintaining the architectural framework designed by Roger Thomas while elevating the guest experience. As the club prepares to reclaim its status as one of the highest-grossing nightclubs in the world, the message is clear: the energy that defined XS is not just being preserved—it is being evolved.

